A graphene-powered bioelectronic platform enabling rapid, on-demand, non-invasive seizure treatment.
Funded under
Horizon Europe
Duration
1/6/2026 - 30/6/2028
Budget
€ 2,494,115.63

What is the mission of the
CLUSTREL project?

CLUSTREL Project develops an advanced bioelectronic drug-delivery platform that addresses the critical need for rapid intervention in epilepsy, where seizures are caused by abnormal, excessive neuronal firing. The innovation pioneers the use of graphene-based materials for the electrically triggered release of anti-seizure medication. It combines nanotechnology, microelectronics, and biocompatible polymers to create an electro-responsive system capable of storing and releasing bioactive molecules on demand. CLUSTREL Project advances the technology toward clinical readiness by shifting from invasive, direct brain-contact applications to a non-invasive, organism-level device using transmucosal delivery routes.

 

The integrated model is built upon:

Graphene-based materials for electrically triggered drug release

A shift to non-invasive transmucosal delivery routes

Integration of material science, controlled drug release, and closed-loop neuromodulation principles

Future Needs’ role in CLUSTREL

Future Needs primary role focuses on strategic exploitation, business strategy, and communication.

 

Key responsibilities and activities for Future Needs include:

Communication & Visibility – Leading tasks to implement a detailed communication strategy, manage the project's visual identity, and maintain the dedicated website.

Stakeholder Alignment – Leading tasks to ensure market alignment by establishing a Stakeholders Forum involving patients, neurologists, regulators, and industry partners.

Exploitation & Business Planning – Focusing on developing the CLUSTREL’s solution business plan and ensure market uptake

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Project Ambition

CLUSTREL combines nanotechnology, microelectronics, and material science to offer a safer, precise, and patient-friendly treatment option for epilepsy and potentially other neurological disorders. The project’s efforts:

 

  • Deliver an electro-responsive system capable of storing and releasing bioactive molecules on demand.

  • Advance the technology toward clinical readiness using non-invasive delivery routes.

  • Integrate controlled drug release with closed-loop neuromodulation principles.

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